The steps involved in creating and running the stand-alone application in your window-based compluter are as follows: 1 if you don't have MATLAB then install MCRInstaller.exe (this file install the MATLAB component runtime that is indispensable) 2 unzip the file prostatefuzzy.zip in (for example) c:\ 3 from start menu of Windows choose programs, accessories, command prompt 4 in the window of the command promt (DOS) type: c: c:\fismain.exe inputdata.txt fis.fis the output is 0.41453 that is the result for the predefine value of PSA 11, %freePSA 12%, PSAdensity 0.25, age 55 year 5 You can change the variables editing the file inputdata.txt. The first number is PSA, the second is free to total PSA ratio the thirt is PSA density and the last one is age. You can add other cases adding other rows. in the file prostatefuzzy.zip there are those files: fis.fis (this is the crucial file for the neurofuzzy system for prostate cancer diagnosis) fismain.ctf fismain.exe (this is the executable) fismain_main.c fismain_mcc_component_data.c inputdata.txt (this is the file with input data: PSA, %freePSA, PSAdensity and age) readme.txt (it is this file)